| | | Updates from the UCI Office of Research |
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| Important NIH Update: New Application Structure for International Collaborations (NOT-OD-25-155) |
| The National Institutes of Health (NIH) announced significant changes to the application and award structure for grants involving international collaborations (NOT-OD-25-155). NIH published an article on Sept. 18, 2025, stating that “effective for due dates on or after Jan. 25, 2026, competing applications must be in response to a funding opportunity using a new grant type when requesting NIH funding for one or more foreign components.”
NIH is developing additional resources, FAQs, and training materials for these new activity codes. Sponsored Projects will distribute updates as they become available. Please reach out to Paul Lekutai at plekutai@uci.edu or Jeff Warner at warnerj@uci.edu if you have any questions. | |
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| Sign up for the Office of Research Listserv |
| | To keep up with the latest updates from the Office of Research amid all the federal funding changes, be sure to subscribe to the CG-News listserv. Sign up by sending a blank email to cg-news+subscribe@uci.edu. | |
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| Due to shifts in the federal agency funding landscape, do not sign any certifications or acknowledgments, complete any surveys, or respond regarding grant compliance, change in abstract or scope of work, or project activities. Instead, forward such communications to Jeff Warner, Senior Director, Sponsored Projects Administration. Authorized Organizational Representatives (AORs) in the Office of Research will handle these matters. If you have trouble getting in touch with your Sponsored Programs offices/Contracts and Grants office, contact Nancy Lewis, Associate Vice Chancellor for Research Administration. Learn more about the impact of federal executive orders and directives on federal grants and contracts.
For other questions or concerns, contact Paul Lekutai, Director, Federal and Non-Federal Sponsored Projects, or Jeff Warner.
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| School of Medicine Applications for Bridge Funding Due Oct. 24 |
| Please note that the next UC Irvine Office of Research deadline for Bridge Funding is Friday, Oct. 31, 2025. Complete applications must include a signed letter of support by your department chair showing financial commitment. Bridge Funding applications are due to the School of Medicine Office of Research by Friday, Oct. 24, 2025.
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| New Tool to Explore NIH Grant Opportunities
Familiarize yourself with the new Explore NIH Grant Opportunities tool. Use its NIH-specific filters, sort, and advanced search options to help you quickly identify funding opportunities posted on Grants.gov. Starting in October 2025, Grants.gov is the single official source for NIH notices of funding opportunities (NOFOs). NIH will no longer post NOFOs in the NIH Guide for Grants and Contracts. The NIH Guide will continue as your primary source for policy and informational notices.
Highlighted Topics
Consider NIH’s centralized list of highlighted topics for your next investigator-initiated grant application. Each topic represents a selected research priority area within one or more NIH Institutes, Centers or Offices (ICOs) that may or may not have dedicated funding. Check the list regularly as new topics are added in the coming months and beyond. Read more about highlighted topics in the August 2025 NIH Extramural Nexus article. | |
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| Accepting Applications for the UC Irvine School of Medicine Clinical Trialist Training Program |
| The School of Medicine’s Office of Research is pleased to offer the Clinical Trialist Training Program (CTTP). The goal is to increase the number of School of Medicine faculty who can be principal investigators on externally funded clinical trials through a two-year partnership program with a senior investigator already running clinical trials. In addition, the trainees will be provided with educational resources to provide the foundational knowledge required for clinical trial administration.
Eligibility:
- Interest in serving as a principal investigator on clinical trials
- Any faculty appointment in the School of Medicine with an active clinical practice
- Commitment from department chair or division chief to dedicate 10% FTE to clinical trial activities
- Commitment from a senior investigator already engaged in clinical trials to serve as a mentor and support the mentee in developing an independent clinical trial portfolio (incentive will be provided to the senior investigator for their commitment)
Visit the CTTP website to learn more and apply. Deadline: Monday, Nov. 10, 2025 | |
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| Save the Date: 2026 Faculty Research Retreat |
| The 2026 School of Medicine Faculty Research Retreat will be held on Thursday, March 5, 2026, from 8:30 a.m. to 7 p.m at Beall Applied Innovation. Registration and comprehensive information about the event will be available soon on the retreat website.
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| FAQ Available for NIH Policy on AI in Research and Limit of Six Applications Per Year |
| | NIH released a notice that details their policy on AI in research and limits applications to six per calendar year. This policy is effective Sept. 25, 2025. There is now an FAQ available that provides clarifications about this new policy. | |
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| Physician Scientist Collective Network Hosts Miguel Villalona, MD |
| Navigating Through Research and Administration in Academic Medicine: The Pursuit of a Dream, Decision Points and Reflections on the Paths Not Taken, by Miguel Villalona, MD, Professor and Chief, Division of Hematology-Oncology, Department of Medicine, UC Irvine School of Medicine; Deputy Director, UCI Chao Family Comprehensive Cancer Center
Thursday, Oct. 23, 4 to 5 p.m.
Via Zoom | | Back to top | | | |
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| Kei Igarashi, PhD (Anatomy & Neurobiology), received an NIH R01 titled, “Circuit vulnerability of the lateral and medial entorhinal cortices in tauopathy models of Alzheimer's disease.” No treatment currently exists for Alzheimer’s-induced impairments of memory formation, a devastating symptom contributing to the massive toll of the disease. This project will investigate vulnerable neuronal types to tauopathy using tauopathy mouse models. The project is expected to yield advances towards the development of therapeutics to rescue memory function in AD.
Do you or someone on your team have research-related good news to report (e.g., research funding/award, publication, other accolade)? We would like to know! Please fill out this short Good News submission form. | | Back to top | | | |
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| Find funding opportunities for trainees, postdocs and early career faculty, and all faculty. For more funding opportunities and resources to help in your funding search, visit the Funding Opportunities page.
The Research Development Unit (RDU) has created lists of intramural funding opportunities and foundation funding opportunities. If you have additional opportunities that should be included, contact the RDU.
Considering applying for a Limited Funding Opportunity? Typically, you submit a pre-proposal to the Office of Research via UCI Review. If the opportunity is not listed, contact the RDU.
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| | Postdocs & Early Career Faculty Funding Opportunities | |
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Graduate or Postdoc Position - NINDS T32 Training Program in Epilepsy Research
Graduate student nominees must have completed at least two years of academic training by July 1, 2024 (i.e., beginning their third or fourth year of study). Postdocs should be in the first two years of training. Apply here.
Deadline: Oct. 3, 2025, 5 p.m.
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| NIH K12 Early-Career Scholar Award |
| The UC Irvine Institute for Clinical & Translational Science (ICTS) has an open call for applications to the NIH-funded K12 award, intended to support early-career faculty for a period of mentored career development in preparation to transition to research independence or enable and expand the candidate’s potential to make significant contributions in the biomedical, behavioral and clinical translational sciences.
This award requires the candidate to hold a full-time junior faculty appointment above the clinical instructor level, and devote a minimum of 75% research effort of that appointment to the K12 program (50% for surgeon-scientists). Our goal is to increase the quantity and quality of exceptionally gifted clinical researchers and translational scientists throughout the training pipeline. Visit the ICTS website for further details and eligibility information. Apply here.
Deadline: Oct. 5, 2025
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| Limited: W. M. Keck Foundation Bridge Funding Initiative for PI/PhD student partnerships |
| The W. M. Keck Foundation has announced a one-time bridge funding program for up to six Faculty/PhD student pairs conducting research that fits within their focus on basic research that enables pioneering discoveries creating new knowledge. Funding is $200,000 over two years per partnership. Keck funds basic research in STEM fields.
Eligibility: PI is Assistant or Associate Professor as of January 2026 and student will be enrolled in PhD program for next two years (i.e., through January 2028).
Interested applicants are asked to submit a preliminary concept paper to the Office of Research (OR) via UCI Review.
Deadline: Oct. 10, 2025
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| The University of California President’s Postdoctoral Fellowship Program |
| The University of California President’s Postdoctoral Fellowship Program (PDF) offers postdoctoral research fellowships and faculty mentoring to outstanding scholars in all fields whose research, teaching, and service will contribute to diversity and equal opportunity.
Applicants must receive a PhD or terminal degree from an accredited university before the start of their fellowship. Fellowships are awarded for research conducted at any of the UC’s 10 campuses. Each award is for a minimum of 12 months and may be renewable for an additional term upon demonstration of academic/research productivity. Apply here.
Deadline: Nov. 1, 2025 | |
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| A.P. Giannini Foundation Postdoctoral Research Fellowship and Leadership Award |
| The A.P. Giannini Foundation invites physician-scientists and junior researchers with three to 36 months of postdoctoral research experience to apply to the 2026 Postdoctoral Research Fellowship & Leadership Award. Postdoctoral researchers are eligible to apply to the 2026 program if they have completed no less than three months and no more than three years in their mentor’s laboratory as of Dec. 31, 2025.
The Fellowship and Leadership Award supports innovative research in the basic sciences and applied fields and trains fellows to become established investigators and to pursue scientific leadership positions in academia, industry, public and non-traditional career pathways. Research projects should advance the translation of biomedical science into preventions, treatments and cures for human diseases.
For questions about the application process, reach out to Dr. Leslie Thompson.
Deadline: Nov. 6, 2025, 3 p.m. | |
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| | All Faculty Funding Opportunities | |
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UCI Alzheimer’s Disease Research Center - Call for Developmental Grant ProposalsThe Alzheimer’s Disease Research Center (ADRC) is pleased to announce the availability of funding for developmental projects. Grants of up to $100,000/year (direct costs) and 1–2 years may be proposed. This funding competition is open to all UC Irvine faculty members (senate and non-senate), with preference for investigators who are pre-tenured and new to the field of Alzheimer’s disease and related disorders (ADRD) research. Apply here. Deadline: Oct. 17, 2025, 5 p.m. | |
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| ICTS Translational Science Pilot Studies Award |
| The UC Irvine Institute for Clinical and Translational Science (ICTS) is pleased to announce a new call for pilot applications for the ICTS Translational Science Pilot Studies Award Program. One-year awards in the amount of $40,000 will be conferred in this round. The funding period is from July 1, 2026, to June 30, 2027.
The ICTS Translational Science Pilot Studies Awards are intended to provide investigators with support to engage in proof-of-concept or preliminary research that addresses a common roadblock or bottleneck in translational research. Projects are expected to inform a subsequent application for extramural funding to extend the findings, which should be generalizable across multiple diseases and lead to improved efficiency or effectiveness of future translational research.
To be eligible to apply for Pilot Studies Awards, the Principal Investigator or co-Investigator MUST attend a workshop and be an ICTS Member.
Pre-application Deadline: Nov. 3, 2025 | |
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| Advancing Technologies for Spatiotemporal Omics in Live Tissue |
| Chan Zuckerberg Biohub Network and the Chan Zuckerberg Initiative invite applications for two-year initial research projects that merge cutting-edge engineering with deep biological inquiry to illuminate the dynamic molecular landscape of health and disease, unlocking new frontiers in high-precision interventions. This RFA represents a strategic investment in transformative research with the potential to drive breakthroughs that significantly advance our health. Learn more about Advancing Technologies for Spatiotemporal Omics in Live Tissue.
Deadline: Nov. 13, 2025, 2 p.m. | |
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| Implementation of Synthetic Biology Principles in Immunology |
| Chan Zuckerberg Biohub Network and the Chan Zuckerberg Initiative invite applications for two-year initial research projects that harness synthetic biology to revolutionize our understanding and treatment of immune-related disorders. This RFA represents a strategic investment in transformative research that has the potential to yield breakthroughs with far-reaching impact on public health. Learn more about the Implementation of Synthetic Biology Principles in Immunology.
Deadline: Nov. 13, 2025, 2 p.m. | |
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| Forecasted NIH Opportunity: Biomedical Technology Optimization and Dissemination Center (BTOD) |
| The National Institute of General Medical Sciences (NIGMS) Biomedical Technology Optimization and Dissemination Centers (BTOD) program supports optimization of late-stage technologies that have demonstrated laboratory feasibility. The centers will move the technologies to the point where they can be widely used and will promote their dissemination within the biomedical research community. NIGMS intends to reissue a Notice of Funding Opportunity to continue to support the BTOD Centers program. Learn more.
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| | | Upcoming Seminars & Events |
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| Department of Biological Chemistry BC Seminar Series |
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Microenvironmental Regulation of Breast Cancer Initiation and Progression, by Kai Kessenbrock, PhD, Assistant Professor, Department of Biological Chemistry, UC Irvine School of Medicine
Wednesday, Oct. 1, 11 a.m. to Noon
Location: Plumwood House / Showa Denko Lecture Hall
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| Ethics in Dementia Care: Past, Present and Future, by Joshua D. Grill, PhD, Professor, Department of Psychiatry & Human Behavior, UC Irvine School of Medicine. Hosted by the UC Irvine Institute for Memory Impairments and Neurological Disorders.
Thursday, Oct. 2, 11 a.m.
Location: Natural Sciences I, Room 1114
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| 2025 Third Annual Symposium for the Center for Neurotherapeutics: "Shifting Paradigms in Neurotherapeutics" |
| The 2025 Third Annual Symposium for the Center for Neurotherapeutics will feature speakers from across the country who will discuss different topics related to translational neuroscience research. Register for this FREE symposium by Wednesday, Oct. 1.
Friday, Oct. 3, 8 a.m. to 6 p.m.
Location: Susan & Henry Samueli College of Health Sciences, Sue Gross Auditorium, 845 Health Sciences Quad, Irvine, CA 92697 | |
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| Science Day x Stem Cell Awareness Day |
| Join the Sue & Bill Gross Stem Cell Research Center for Stem Cell Awareness Day! Though registration for Science Day activities for kids is now closed, guests are welcome to join building and lab tours from 11 a.m. to 3 p.m. For questions, contact Kristina Yan.
Saturday, Oct. 4, 11 a.m. to 3 p.m.
Location: Sue & Bill Gross Hall, 845 Health Sciences Road, Irvine, CA 92617 | |
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| Experimental Pathology Research in Progress |
| Examining White Matter Aging in Down Syndrome with Alzheimer's Disease, by Justine Silva, Graduate Student, Elizabeth Head, PhD, Lab, Department of Pathology & Laboratory Medicine, UC Irvine School of Medicine
Monday, Oct. 6, 11 a.m. to Noon PT
Location: Hybrid event at Plumwood House / Showa Denko Lecture Hall and via Zoom
Meeting ID: 955 3602 935 | Passcode: 998046 | |
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| Department of Physiology & Biophysics Research in Progress Seminar |
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|  Olga Orozco
Graduate Student
Michael Hicks, PhD, Lab
|  Samuel Kim
Graduate Student
Lisa Wagar, PhD, Lab
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Capturing the Myogenic Waves of Development with Multiomics Single-cell Optimal Transport, by Olga Orozco
Investigating Immune Cell Targets of Lipid Nanoparticle Based mRNA Vaccines, by Samuel Kim
Wednesday, Oct. 8, 4 to 5 p.m.
Location: Plumwood House Lecture Hall | |
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| 10x Genomics Single Cell Data Analysis Workshop |
| In this workshop, you will be introduced to the single cell gene expression analysis journey. Learn more at the UCI Genomics Research & Technology Hub website. This event is free but registration is required.
Thursday, Oct. 9, 10 a.m. to 4 p.m.
Location: UCI Interdisciplinary Science & Engineering Building (ISEB) - Room 1010
Morning Refreshments & Lunch Provided
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| Applying for an NIH Loan Repayment Program (LRP) Award? Don’t Miss the Upcoming Webinar! |
| You're invited to join NIH Loan Repayment Program (LRP) staff for a live Technical Assistance Webinar. This session will provide LRP applicants with an in-depth look at the application process and more. The current LRP application cycle opened on Sept. 1, 2025, and will close on Nov. 20, 2025.
Thursday, Oct. 9, 11 a.m. to 1 p.m.
Via Webinar
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| UC Irvine Center for Aging Research in Down Syndrome Research Seminar Series |
| From Development to Neurodegeneration: Biological, Environmental and Psychosocial Influences on Cognition in Down syndrome, by Christy Hom, MD, PhD, Associate Professor, Department of Psychiatry & Human Behavior, UC Irvine School of Medicine. Hosted by the UC Irvine Center for Aging Research in Down Syndrome (CFAR-DS).
Friday, Oct. 10, 11 a.m. PT
Via Zoom
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| Noel Drury, M.D. Institute for Translational Depression Discoveries Special Fall Speaker Series |
| Neural Circuit Mechanisms Underlying Depressive-like States, by Jessie Muir, PhD, Postdoctoral Scholar, Princeton University. Hosted by the UC Irvine Noel Drury, M.D. Institute for Translational Depression Discoveries.
Monday, Oct. 13, 10 to 11 a.m.
Location: Thorp Conference Center, 4001 Gross Hall | |
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| Monthly on Mondays | Faculty Development Series |
| Personal Finance, presented by David Brownstone, PhD. Monthly on Mondays, presented by Nimisha K. Parekh, MD, and Brian Cummings, PhD, associate deans of faculty development, is a monthly seminar series covering a wide range of topics on faculty development.
Monday, Oct. 13, 5:15 to 6:15 p.m.
Via Zoom | |
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| Effective Mentorship – Fall 2025 Short Course |
| Presented by the UC Irvine Office of Research, GPS-STEM, the Institute for Clinical & Translational Science, and the Department of Physiology & Biophysics, this course is for current PhD students and postdocs. Learn about aligning expectations, what it means to be a good mentor and developing a mentor philosophy.
Tuesday, Oct. 14, 10 a.m. to 2:30 p.m. (Lunch provided) & Tuesday, Oct. 28, 10 a.m. to Noon
*Both days required
Location: NatSci I – 1114 | |
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| Rady Children's Health and UC Irvine Distinguished Lecture Series |
| Personalized Research Methodologies That Enhance Pediatric Healthcare Outcomes, by Amir Rahmani, PhD, Co-founder & Chief Scientific Officer, Centralive, Professor of Computer Science, Electrical Engineering & Computer Science, and Nursing, University of California, Irvine (UCI) and Associate Director, UCI Institute for Future Health (IFH)
Wednesday, Oct. 15, Noon to 1:15 p.m.
Via Zoom
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| Physiology & Biophysics Seminar Series |
| Think Positively: Novel Mechanisms of Modulating Synaptic Plasticity and Pain, and Implications for Brain Disease, by Kevin T. Beier, PhD, Associate Professor, Department of Physiology & Biophysics, UC Irvine School of Medicine Thursday, Oct. 16, 4 to 5 p.m. PT
Location: Hybrid event at Plumwood House Lecture Hall and Via Zoom
Contact Claire Chen to join via Zoom.
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| Stem Cell Seminar Lecture Series |
| Mechanobiology of hiPSC Heart Muscle Cells, by Beth Pruitt, PhD, Professor and Mehrabian Chancellor’s Chair, Department of Bioengineering, UC Santa Barbara. Hosted by the UCI Sue & Bill Gross Stem Cell Research Center.
Friday, Oct. 17, 11 a.m. to Noon
Location: Gross Hall, Thorp Conference Center (4th Floor)
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| SIIM-CAIMI 2025 Conference on AI in Medical Imaging |
| Join the SIIM-CAIMI 2025 Conference on Artificial Intelligence in Medical Imaging, a high-energy, research-driven meeting uniting clinicians, researchers and innovators to push imaging AI from the lab to real-world impact. This event is co-hosted by Peter Chang, MD, director of UC Irvine’s Center for Applied Artificial Intelligence Research (A²IR). SIIM-CAIMI features two days of cutting-edge talks, live discussions and scientific abstracts on foundation models, segmentation and next-gen clinical workflows. Learn more about the SIIM-CAIMI Conference.
Monday, Oct. 20, 7 a.m. to 7:30 p.m. & Tuesday, Oct. 21, 7 a.m. to 3 p.m.
Location: UCI Beall Applied Innovation @ the Cove, 5270 California Ave #100, Irvine, CA 92617 | |
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| Third Annual Paolo Sassone-Corsi Lectureship | Michael Greenberg, PhD |
| How Nature and Nurture Conspire to Control Brain Development and Function, by Michael Greenberg, PhD, Nathan Marsh Pusey Professor of Neurobiology, Professor of Neurology, Director, Hock E. Tan and K. Lisa Yang Center for Autism Research, Harvard Medical School
The Paolo Sassone-Corsi Lectureship is presented and organized by the Center for Epigenetics & Metabolism in honor of Paolo Sassone-Corsi's legacy in epigenetics and metabolism.
Monday, Oct. 20, 5 to 8 p.m.
Location: Sue Gross Auditorium, Susan & Henry Samueli College of Health Sciences, 856 Health Sciences Quad, Irvine, CA 92697 | |
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| Noel Drury, M.D. Institute for Translational Depression Discoveries Monthly Speaker Series |
| Mechanisms and Actions of Dopaminergic Agonists in the Treatment of Depression, by Michael Browning, MD, PhD, Professor of Computational Psychiatry, Department of Psychiatry, University of Oxford. Hosted by the UC Irvine Noel Drury, M.D. Institute for Translational Depression Discoveries.
Wednesday, Oct. 22, 10 to 11 a.m. PT
Location: Hybrid event at Thorp Conference Center, 4001 Gross Hall and Via Zoom | |
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| Noel Drury, M.D. Institute for Translational Depression Discoveries Special Fall Speaker Series |
| Harnessing Neuromodulation to Investigate Amygdala Encoding of Affect, by Sean Piantadosi, PhD, Postdoctoral Scholar, University of Washington. Hosted by the UC Irvine Noel Drury, M.D. Institute for Translational Depression Discoveries.
Thursday, Oct. 23, 10 to 11 a.m. PT
Location: Herklotz Conference Room, Center for the Neurobiology of Learning and Memory, 300 Qureshey Research Lab, Irvine, CA 92697 | |
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| UCI SKIN: A Skin Biology Resource Center Distinguished Speaker Series |
| Mapping Stromal-Immune Communication in Cutaneous T-Cell Lymphoma, by Courtney Johnson, MD, PhD, Clinical Associate, Department of Dermatology, Johns Hopkins University School of Medicine. Hosted by the UCI Sue & Bill Gross Stem Cell Research Center.
Friday, Oct. 24, 11 a.m. to Noon
Location: Hybrid event at Gross Hall, Thorp Conference Center (4th Floor) and Via Zoom
Contact Kristina Yan to join via Zoom.
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| ICTS K-Club Grant Writing Series |
| The Institute for Clinical and Translational Science (ICTS) has coordinated a K-Club grant writing series intended for early- career faculty and postdoctoral scholars preparing to submit applications for NIH Mentored Career Development awards . These awards are designed to promote the career development of scholars looking to transition to research independence.
- Workshop 1: Introduction: Overview of the RFA and submission materials | Oct. 30, 9 to 10:30 a.m.
- Workshop 2: Assembling Your Application: Setting yourself up for a strong application and review | Nov. 6, 9 to 10:30 a.m.
- Workshop 3: Specific Aims, Career Development Plan & Mentor Qualification: Writing clear aims and assembling a qualified mentoring team | Nov. 13, 9 to 10:30 a.m.
- Workshop 4: K Award Panel Discussion: Q&A with current K Awardees about the grant process | Nov. 20, 9 to 10:30 a.m.
Registration Deadline: Oct. 28, 2025
Location: UCI Campus, Hewitt Hall, Large Conference Room, Room 1042
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| UC Irvine Center for Neuropolitics 2025 Symposium |
| The New Language of Politics: Populism, Authoritarianism, Fascism and Beyond, with multiple speakers, including keynote speaker Steven Levitsky, PhD, Professor of Government, Harvard University. This event is hosted by the UC Irvine Center for Neuropolitics. Register today for this FREE, virtual lecture! Friday, Oct. 31, 8 a.m. to Noon PT
Via Zoom
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| Grand Rounds and CME Symposia |
| | For Continuing Medical Education (CME) opportunities, view the weekly Grand Rounds & CME Symposia email. | | Back to top | | | |
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| Do you have an open research-related position you would also like announced in Research Insider? Please fill out this form to have your open position listed.
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| What kind of grant support does the School of Medicine Research Development Unit provide? |
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| What kind of grant support does the RDU provide to Physician Scientists? |
| Along with the general grant support the RDU provides (outlined above), there are multiple programs available outlined on the Physician Scientist Resources page. - Physician Scientist Collective: Monthly seminar series with visiting speakers
- Physician Scientist Pathways Certificate Course: Six-week, 12-hour hybrid course that introduces clinicians to research pathways
- Physician Scientist Training Program (PSTP): Helps physician scientists apply for their first K award
- Dean’s K Scholar: Provides awardees the protected time and mentorship needed to obtain NIH K/ equivalent funding
- Clinical Trialist Training Program (CTTP): Supports junior faculty on externally funded clinical trials through a 2-year partnership program with senior investigators already running clinical trials
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