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Background:
The Department of Pathology & Laboratory Medicine will send out certain specialty tests that were previously offered in-house: multiple sclerosis panel, oligoclonal bands, and CSF protein electrophoresis, effective immediately. These send out tests are available with similar turnaround time.
The recommended send out test for multiple sclerosis is the Oligoclonal Band Profile which includes CSF IgG index and oligoclonal band detection. Oligoclonal bands, when performed by isoelectric focusing, are present in approximately 95% of patients with multiple sclerosis. The Department of Pathology & Laboratory Medicine is working to validate and provide this service in-house in the near future.
Methodology and reporting:
| Multiple Sclerosis Panel (MSPN) |
XMSPN
CSF Oligoclonal Band Profile
(ARUP test 0080440) |
1-4 days |
| Oligoclonal bands (OLIGO) |
XOLIGO
CSF Oligoclonal bands
(ARUP test 0081135) |
1-4 days |
Effective date: November 14, 2018
Specimen requirement and testing information: http://www.aruplab.com/testing
Specimen: CSF AND serum separator tube or plain red. Serum specimen should be drawn within 48 hours of CSF collection. Transport 1.5 mL CSF (min: 0.7 mL) AND transfer 1 mL serum to ARUP Standard Transport Tube. (min: 0.5 mL).
Test methodology: Isoelectric focusing/electrophoresis/nephelometry
Test code: XMSPN, XOLIGO
Stability:
Ambient: 8 hours
Refrigerated: 1 week
Frozen: 1 year
Turnaround time (TAT):
STAT: Not available
Routine: Set-up days: Sunday - Saturday
A summary of all tests offered by our laboratory services can be found here: http://www.pathology.uci.edu/services/index.asp
Sincerely,
Bridgit O. Crews, PhD, DABCC
Director
Clinical Chemistry & Toxicology
Edwin S. Monuki, MD, PhD
Chair
Department of Pathology & Laboratory Medicine
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