August 15, 2023
Announcements
 
Open Research Positions in UCI School of Medicine 
Do you have an open laboratory position currently posted on UCI Recruit that you would like announced in Research Insider? Please fill out this form to have your position listed in our new section, which we will be dedicating to open research opportunities in the School of Medicine. 
Submit Form

 
NIH Application Instruction Updates Data Management and Sharing (DMS) Costs (NOT-OD-23-161)
This notice updates the NIH application instructions for submitting requests for Data Management and Sharing costs in a single line item. Currently, the NIH How to Apply - Application Guide states that costs to support activities described in the DMS plan, including personnel costs, must be noted on the R&R Budget Form as a single line item. The line item must be used only for DMS costs and cannot be combined with any “Other” costs. If no costs will be incurred, the applicant must enter “0” in the funds requested column. These previous instructions will be rescinded effective October for due dates on or after Oct. 5, 2023.

Effective for applications submitted for due dates on or after Oct. 5, 2023, NIH will no longer require the use of the single DMS cost line item. NIH recognizes that DMS costs may be requested in many cost categories. Therefore, in line with standard budget instructions, DMS costs must be requested in the appropriate cost category, e.g., personnel, equipment, supplies, and other expenses, following the instructions for the R&R Budget Form or PHS 398 Modular Budget Form, as applicable. While the single cost line item is no longer required, NIH will require applicants to specify estimated DMS cost details within the “Budget Justification” attachment of the R&R Budget Form or “Additional Narrative Justification” attachment of the PHS 398 Modular Budget Form, pursuant to the instructions.

Updates to the NIH How to Apply – Application Guide will be published prior to the Oct. 5, 2023, effective date. Read the full update.

 
The Dean’s Distinguished Lecture Series Returns for 2023-24!
Ardem Patapoutian, PhDThe School of Medicine Office of the Dean is delighted to announce that 2021 Nobel Laureate in Medicine Ardem Patapoutian, PhD, will present the first lecture of the year: “How Do You Feel? Molecules That Sense Touch.

Oct. 17, 6:30 p.m.
Location: The Beckman Center, 100 Academy Way, Irvine, Calif. 

Refreshments will be provided.

RSVP
 
Interested in submitting for an NIH multi-component grant?
If you are interested in submitting for an NIH multi-component grant, such as the P or U mechanism, please remember to reach out to Dr. Al La Spada, Associate Dean for Research Development (alaspada@uci.edu). He can guide you through the process and connect you with potential collaborators.

Also, remember that the Research Development Unit (RDU) provides
project management support for these mechanisms.
To request RDU services, submit this Grant Support Request intake form. There is also an incentive program for these submissions, with more details in this Incentive Program intake form.
 
Second Call for New Proposals: Basic and Translational Research Programs Requiring Wet Lab Space
There is a second call for new proposals for basic and translational research programs requiring wet lab space. This is a follow-up call to the original RFP in 2021. This call is for new proposals.

Please submit your proposals for research programs to Shauna Stark, starks@hs.uci.edu by Sept. 1, 2023. The School of Medicine’s Office of the Dean will reach out to you with recommendations for revision so they can be forwarded to the Office of the Vice Chancellor for Health Affairs by Oct. 15, 2023.

Deadline: Friday, Sept. 1, 2023
 
Register for Fall Course on Modern Topics in Gene Editing and Gene Therapy 
The Department of Biomedical Engineering and the UCI Center for Translational Vision Research (CTVR) at the School of Medicine, are proud to offer an exciting course this fall on modern topics in gene editing and gene therapy. Register now for this fall! 

BME 295/195: Modern Topics in Gene Editing and Gene Therapy. This 10-week, 4-unit course is geared toward PhD students and advanced undergraduates and will give students three hours of contact with the instructor during class each week. Students will also have one hour of group discussion without the instructor in preparation for class. In addition to these commitments, students will be responsible for preparing for class by completing reading and assignments before each class. The class will cover topics such as history of programmable nucleases, with an emphasis on CRISPR, editing and manipulating genomes using programmable nucleases and CRISPR technologies, and gene therapy applications, focusing on precision gene editing to correct disease mutations. 
Good News!
 
We have been collecting information about new awards sent in by the School of Medicine research community and have created this space to share the news.

  • Al La Spada, MD, PhD, Pathology, and Wei Li, PhD, Biological Chemistry, and their colleague Carlo Rinaldi, received a California Institute of Regenerative Medicine (CIRM) grant to investigate the "Role of ataxin-3 polyadenylation site selection in ALS neuron toxicity and disease pathogenesis." 

  • Sunmin Lee, ScD, MPH, Medicine, was awarded a supplement research grant from the NIMHD R01 “Stress, Sleep, and Cognitive Function among Asian Americans.”  These studies will elucidate health issues of this understudied group and identify modifiable factors that will serve as targets for intervention to reduce sleep disparities among Asians.

  • Dongbao Chen, PhD, Obstetrics and Gynecology, was awarded a minority supplement to support a graduate student on his NHLBI R01,“Actions of Estrogen on Uterine Artery Endothelium.” His team’s work will advance our understanding of estrogens and uterine blood flow biology, informing new pathways to assist the development of new strategies for combating preeclampsia and will also shed light on the understanding of the cardiovascular protective effects of estrogens.

Have you or someone on your research team received a new grant, i.e., research funding? The School of Medicine Office of Research would like to know! Please fill out this short New Funding/Grant Survey form.
Funding Opportunities
 
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.).

The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data.

Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research. 
Read the NOFO

First Available Deadline: Thursday, Oct. 5, 2023
Expiration Date: Sept. 8, 2026
 
Postdoctoral Funding Opportunity! A.P. Giannini Foundation Fellowship
The A.P. Giannini Foundation invites physician-scientists and junior researchers with 3 to 36 months of postdoctoral research experience (as of Dec. 31, 2023) to apply to the 2024 Postdoctoral Research Fellowship & Leadership Award.

The Fellowship and Leadership Award supports innovative research in the basic sciences and applied fields and trains fellows to become established investigators and to pursue scientific leadership positions in academia, industry, public and non-traditional career pathways. Research projects should advance the translation of biomedical science into preventions, treatments and cures for human diseases. Applicants with tenure-track research positions or faculty appointments are ineligible.

Fellows receive a competitive stipend for their research training. Candidates may be eligible to obtain additional salary support from their sponsoring institution. Fellows cannot concurrently hold a full fellowship from another source or a federally funded career development award. Fellows receive leadership training and support to maximize their postdoctoral experience. Fellows participate in workshops and receive one-on-one coaching to foster their communication and leadership skills. The Foundation requires that fellows participate in the Leadership Program.

For questions about the application process, reach out to Dr. Leslie Thompson (lmthomps@hs.uci.edu).

Deadline: Thursday, Nov. 9, 2023, 3 p.m.
 
Funding Opportunity to Use NIH All of Us Data to Advance Health Research
The National Institutes of Health (NIH) All of Us Research Program is building one of the largest biomedical data resources of its kind by collecting health data and biospecimens from a diverse cohort of one million or more participants nationwide. The objective is to accelerate health research and medical breakthroughs, enabling individualized prevention, and health care for all of us. 
   
The UCI Genetic Epidemiology Research Institute (GERI) along with the Office of Data and Information Technology, are sponsoring a research funding opportunity for UCI researchers to utilize the NIH All of Us Research Program data to pursue health-related research topics of interest. 

All of Us dataset is one of the richest and most diverse biomedical datasets ever built with over 413,450+ participants, 75% are from communities underrepresented in biomedical research and 45% are from racial and ethnic minority groups. It can be accessed and analyzed through the All of Us Researcher Workbench, a cloud-based research platform as part of the Program’s Research Hub. The Researcher Workbench contains a suite of custom tools for cohort building, data extraction, and statistical or machine-learning analysis.
   
Under this announcement, we intend to fund projects at a maximum level of $2,500 each. Proposals will be evaluated based on their scientific merit. Successful applications are those considered to have a high potential for publications and for future extramural funding. Applicants for this funding opportunity must be full-time UCI faculty including those in the Clinical and Adjunct Research series who have an established account with the NIH All of Us Researcher Workbench. The scope of the proposed research must be planned to be completed within one year.

Applications must be submitted to Jenny Fang at jennyf3@hs.uci.edu. Each applicant is only allowed to submit one application. Please see our PDF for more detailed information on application submission.
  
Deadline: Ongoing
 
For More Funding Opportunities
For more funding opportunities and resources for your funding search, visit the Funding Opportunities page on the new and updated website for the UCI School of Medicine.

For a curated, searchable and filterable list of funding opportunities by NIH in their weekly NIH guide listserv, check out the School of Medicine Funding Search Tool.
Upcoming Seminars & Events
 
CHOC Research Education: NIH Grant Writing & Funding Success Part 2 - with Jessica Lerch, PhD
Speaker: Jessica Lerch, PhD, co-founder of CareerVolt 

Discussion topics:
  • Tips for writing an impactful Aims page
  • Write for your reviewers 

CareerVolt provides one-on-one coaching and bootcamps to accelerate science careers. They support faculty in pursuing goals to publish, get funding and better manage your time and resources.

Wednesday, Aug. 30, noon to 1:15 p.m. 
Register
 
Next-Generation Nanomedicine Keystone Symposia
Nanomedicines have revolutionized our ability to create medicines for previously untreatable diseases as well as novel therapies in a rapid and scalable manner. Despite immense progress, there remains challenges in the field. Join us as we gather nanomedicine specialists with varied backgrounds to spark new collaborations and inspire new innovations. We anticipate that our approach of integrating nanomedicine specialists with varied backgrounds will create a unique environment that will spark new collaborations and inspire new innovations.

To attend in-person, you will need to pay the registration fee for the virtual event through the Keystone Symposia website. During checkout, you will be given the option to RSVP to the In-Person event. There is no additional registration fee for attending in-person.

Sept. 6–8, 2023 
Location: The Beckman Center, 100 Academy Way, Irvine, Calif. 
Register
 
CIRM Alpha Clinic Network 2023 Annual Symposium
UCI’s Alpha Clinic will be hosting the CIRM Alpha Clinic Network 2023 Annual Symposium. Food will be provided and parking is free at this all-day event. More information to come. We hope to see you there! 

Friday, Sept. 8, all day 
Location: UCI Beall Applied Innovation – 5270 California Ave., Irvine, Calif.
Register
 
Making a Difference in Human Subjects Research: Empowering Participants, Engaging Communities, and Protecting Data
​​​​​​Interested in spending two informative days with the HHS Office for Human Research Protections (OHRP) and your fellow colleagues in the human research protection world? If so, make plans to attend this in-person event, highlighting the ethical challenges and opportunities presented by AI technologies and innovations in academic-community partnerships.

Be sure to check out the 
line-up of speakers which includes experts from the NIH Office of Science Policy (OSP). Don’t miss this valuable and engaging opportunity to share challenges and learn best practices on how to manage, share and protect research data from HHS experts and your institutional colleagues.

Sept. 26–27, 2023 
Location: The Michigan League, 911 N. University Ave., Ann Arbor, MI 48109
Register
 
2023 Inaugural Symposium for the UCI Center for Neurotherapeutics
“Exploring the Future of Neurotherapeutics” 
Join the new UCI Center for Neurotherapeutics for its first symposium, hosted by Albert La Spada, MD, PhD, Director, and Robert Spitale, PhD, Associate Director. Learn more about the 2023 Inaugural Symposium for the UCI Center for Neurotherapeutics

Oct. 6, 8 a.m. to 6 p.m.
Location: The Beckman Center, 100 Academy Way, Irvine, Calif.
Register
 
Ion Channel Modulation Symposium Featuring Keynote Address by 2021 Nobel Laureate Ardem Patapoutian
The School of Medicine Office of Research, in conjunction with Sophion Bioscience, invites you to attend the 2023 Ion Channel Modulation Symposium. The Ion Channel Modulation Symposium (ICMS) brings together researchers, scientists and industry professionals from around the world to exchange ideas, share the latest advancements and explore new frontiers in the field. The event will feature talks, poster presentations and excellent networking opportunities. Keynote speaker Ardem Patapoutian, PhD, and a slate of over 20 speakers from labs around the world including UCI faculty Geoff Abbott, PhD, Michael Cahalan, PhD, Steve Goldstein, MD, PhD and Medha Pathak, PhD will be among the presenters.

The ICMS will coincide with the UCI School of Medicine’s Dean’s Distinguished Lecture Series (DDLS), which will feature Dr. Patapoutian as the main speaker. The DDLS community lecture will be Oct. 17 at 6:30 p.m. and the scientific lecture is Oct. 18 at 9 a.m. All events will be at The Beckman Center in Irvine.

Registration for the ICMS is free of charge though there is a cap at 130 participants. If you have any questions, please contact Emily Dawidoff.

Oct. 18–19, 2023
Location: The Beckman Center, 100 Academy Way, Irvine, Calif.  
Register
 
Save the Date! ICTS Workshop: Responsible Conduct of Research
Responsible Conduct of Research (RCR) is increasingly viewed as an essential component of training, regardless of a researcher's source of funding. NIH requires RCR training that involves at least 8 contact hours between participants and faculty. Instruction must be undertaken at least once during each career stage, and at a frequency of no less than once every four years. To meet the NIH requirement, the Institute of Clinical and Translational Science in partnership with the Office of Research will be hosting a full in-person workshop in October: 
  • Friday, Oct. 20, 9 a.m. to 2 p.m.
  • Saturday, Oct. 21, 9 a.m. to 3 p.m.
More information to come by the end of August. If interested, email Marguerite Klumb and she’ll send information once available.

Oct. 20–21, 2023
Location TBA

 
Grand Rounds and CME Symposia
For Continuing Medical Education (CME) opportunities, view the weekly Grand Rounds & CME Symposia email.
Research Resources
 
Drawing a Blank? Samples Can Get You Started!
If you are new to writing grant applications, sometimes seeing how someone else has presented their idea can help as you are developing your own application. Read more about Samples: Applications, Attachments and other Documents.
 
Addressing Rigor in Scientific Studies
As NIH has been emphasizing for more than a decade, the rigor and transparency of a study are key for gleaning the robustness of its results. This includes the design, implementation, analysis and interpretation of experiments. Read more.
 
What kind of grant support does the Research Development Unit (RDU) provide?
 
NIH Biosketch Info Session Recording
The Research Development Unit (RDU) recently held a NIH Biosketch info session. View the recording and slide deck. If you have any questions or would like the RDU to review your biosketch to ensure compliance, please email somrd@hs.uci.edu.
 
Are you considering applying for Limited Funding Opportunities?
In most cases, interested applicants submit a pre-proposal to the Office of Research where a committee reviews all submissions and makes a recommendation to the Vice Chancellor for Research about which proposal should go forward from UCI. Limited opportunities are advertised on fundopp.uci.edu with a link to apply. However, if you do not see a limited opportunity listed, please contact the Research Development Unit. We can relay your application plans to the UCI Office of Research so they are aware of the number of interested PIs/units on campus and, if necessary, coordinate PIs or create a review process.
 
Intramural & Foundation Funding Opportunities Lists
The Research Development Unit (RDU) has created lists of intramural funding opportunities and foundation funding opportunities. If you have additional opportunities that should be included, please do not hesitate to email at somrd@hs.uci.edu.
COVID-19 Information
 
UCI’s COVID-19 information hub, UCI Forward, has been retired. All employee-related information has migrated to the Human Resources Working Well webpage, and student-related information has moved to the Student Health Center webpage. For UCI Health updates, please visit UCI Health's COVID-19 page on SharePoint.
Contribute to Research Insider!
 
Submit your funding opportunities and events to next week's email here: Seminar/Event or Funding Opportunity.
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