July 25, 2023
Announcements
 
Ion Channel Modulation Symposium Featuring Keynote Address by 2021 Nobel Laureate Ardem Patapoutian
The School of Medicine Office of Research, in conjunction with Sophion Bioscience, invites you to attend the 2023 Ion Channel Modulation Symposium. The Ion Channel Modulation Symposium (ICMS) brings together researchers, scientists and industry professionals from around the world to exchange ideas, share the latest advancements and explore new frontiers in the field. The event will feature talks, poster presentations and excellent networking opportunities. Keynote speaker Ardem Patapoutian, PhD, and a slate of over 20 speakers from labs around the world including UCI faculty Geoff Abbott, PhD, Michael Cahalan, PhD, Steve Goldstein, MD, PhD and Medha Pathak, PhD will be among the presenters.

The ICMS will coincide with the UCI School of Medicine’s Dean’s Distinguished Lecture Series (DDLS), which will feature Dr. Patapoutian as the main speaker. The DDLS community lecture will be Oct. 17 at 6:30 p.m. and the scientific lecture is Oct. 18 at 9 a.m. All events will be at The Beckman Center in Irvine. Registration for DDLS is forthcoming.

Registration for the ICMS is free of charge though there is a cap at 130 participants. If you have any questions, please contact Emily Dawidoff.

Oct. 18–19, 2023
Location: The Beckman Center, 100 Academy Way, Irvine, CA 92612 
Register

 
Open Research Positions in UCI School of Medicine 
Do you have an open laboratory position currently posted on UCI Recruit that you would like announced in Research Insider? Please fill out this form to have your position listed in our new section, which we will be dedicating to open research opportunities in the School of Medicine. 
Submit Form

 
Interested in submitting for an NIH multi-component grant?
If you are interested in submitting for an NIH multi-component grant, such as the P or U mechanism, please remember to reach out to Dr. Al La Spada, Associate Dean for Research Development (alaspada@uci.edu). He can guide you through the process and connect you with potential collaborators.

Also, remember that the Research Development Unit (RDU) provides
project management support for these mechanisms.
To request RDU services, submit this Grant Support Request intake form. There is also an incentive program for these submissions, with more details in this Incentive Program intake form.
 
Register for Fall Course on Modern Topics in Gene Editing and Gene Therapy 
The Department of Biomedical Engineering and the UCI Center for Translational Vision Research (CTVR) at the School of Medicine, are proud to offer an exciting course this fall on modern topics in gene editing and gene therapy. Register now for this fall! 

BME 295/195: Modern Topics in Gene Editing and Gene Therapy. This 10-week, 4-unit course is geared toward PhD students and advanced undergraduates and will give students three hours of contact with the instructor during class each week. Students will also have one hour of group discussion without the instructor in preparation for class. In addition to these commitments, students will be responsible for preparing for class by completing reading and assignments before each class. The class will cover topics such as history of programmable nucleases, with an emphasis on CRISPR, editing and manipulating genomes using programmable nucleases and CRISPR technologies, and gene therapy applications, focusing on precision gene editing to correct disease mutations. 
 
New Certification Questions for Senior / Key Personnel on federal proposals
On Aug. 1, 2023, all Senior/Key Personnel on new and in-progress federal and federal flow-through proposals must complete new certification questions in Kuali Research Proposal Development (KRPD). These questions will help UCI meet the federal government’s expectations that grantee institutions submit complete and accurate federal proposals, including ensuring that all Senior/Key Personnel disclose their international engagements in compliance with federal agency disclosure requirements.

Research Engagement and Compliance (REC) and Electronic Research Administration will hold office hours to help answer your questions and to demo how the new process will work in KRPD. Read the full announcement.

Wednesday, July 26, 10 to 11 a.m.
Join Zoom

 
Apply to the CFCCC Mentorship, Education and Training (MET) Program

The Chao Family Comprehensive Cancer Center (CFCCC) Cancer Research Training & Education Coordination (CRTEC) is accepting applications for the Mentorship, Education and Training (MET) Program.

The CFCCC MET Program is a year-long mentoring program designed to engage the expertise of senior CFCCC members with the goal of supporting junior and mid-career CFCCC faculty (basic, clinical and population science) and to catalyze strategies for overcoming career and scientific challenges.

Learn more about the MET Program, including details on how to apply. Apply now until Aug. 15, 2023.

 
Request for Information on Catalyzing the Development and Use of Novel Alternative Methods to Advance Biomedical Research
The National Institutes of Health (NIH) seeks public input on challenges and opportunities for the further development and use of novel alternative methods (NAMs) in biomedical research. NIH investment in these methods have proven beneficial tools across basic and clinical research studies, being developed and applied to interrogate cancer, diabetes, cardiovascular disease, Alzheimer's disease, infectious disease, rare diseases and more. Each NAM approach has unique strengths and limitations that vary depending on the specific research question being addressed.

To identify areas in which the development and use of NAMs provide the most value to biomedical research, NIH sought the assistance of the Advisory Committee to the Director (ACD), an advisory group that provides advice on matters pertinent to NIH mission responsibilities in the conduct and support of biomedical research, medical science and biomedical communications. The purpose of this request is to inform the NIH and the development of the ACD’s recommendations on high-priority areas for future investment.

To support the activities of the ACD Working Group, NIH is requesting information from interested individuals and communities on challenges and opportunities for the development and use of NAMs in biomedical research. Input sought includes, but is not limited to, feedback on the following:

  • The use of novel alternative methods to study human biology, circuits, systems, and disease states.
  • Approaches for catalyzing the development and validation of novel alternative method technologies.
  • Strategies for maximizing the research value of novel alternative method technologies.

All comments must be submitted electronically here. It is not necessary to address each question/item. The comment period will close on August 16, 2023.

Deadline: Wednesday, Aug.16, 2023
 
Second Call for New Proposals: Basic and Translational Research Programs Requiring Wet Lab Space
There is a second call for new proposals for basic and translational research programs requiring wet lab space. This is a follow-up call to the original RFP in 2021. This call is for new proposals.

Please submit your proposals for research programs to Shauna Stark, starks@hs.uci.edu by Sept. 1, 2023. The School of Medicine’s Office of the Dean will reach out to you with recommendations for revision so they can be forwarded to the Office of the Vice Chancellor for Health Affairs by Oct. 15, 2023.

Deadline: Friday, Sept. 1, 2023
Good News!
 
We have been collecting information about new awards sent in by the School of Medicine research community and have created this space to share the news.

  • Emma Lessieur Contreras, PhD, Ophthalmology – Received a K99/R00 NEI MOSAIC Program Postdoctoral Career Transition Award to Promote Diversity to study retina-derived extracellular vesicles in diabetic retinopathy and their potential role in pathogenesis and therapy.

  • Raymond Wang, PhD, Pediatrics – His proposed R01 studies funded by NICHD will evaluate a multimodal gene therapy approach in the canine model of MPS I, a lysosomal storage disorder historically known as Hurler, Hurler-Scheie, and Scheie syndromes. The goal is to simultaneously remedy multiple refractory aspects of the disease, paving the way toward future therapy for people with MPS I.

  • Alexa Tierno, MS, Anatomy & Neurobiology – Received an NIH F31 NRSA award to image progressive circuit reorganization after traumatic brain injury. She is a graduate student in Dr. Robert Hunt’s lab.

  • Fawaz Al Almmary, MD, PhD, Medicine – A new arrival to UCI, will begin research on his NIDDK-funded K23 project, Telemedicine for Evaluation and Counseling of Living Kidney Donor Candidates.

Have you or someone on your research team received a new grant, i.e., research funding? The School of Medicine Office of Research would like to know! Please fill out this short New Funding/Grant Survey form.
Funding Opportunities
 
UC Noyce Initiative 2023 Call for Applications
The UC Noyce Initiative is a partnership between five University of California campuses (Berkeley, Davis, Irvine, San Francisco, Santa Barbara) that honors the legacy of Ann S. Bowers and Robert N. Noyce by advancing computing, information science and engineering for the benefit of society. To further this aim, the UC Noyce Initiative intends to support research efforts that are innovative, have the potential for high-impact, and hold a strong promise for follow-on funding. The UC Noyce Initiative is particularly interested in supporting high-risk, high-reward research that typically does not qualify for traditional or federal funding agencies. In 2023, the UC Noyce Initiative requests proposals in two thematic focus areas: (1) Computational Health; (2) Privacy and Security.

Researchers may apply for either a Multi-Campus Partnership Award (up to $1M over 2 years) or a Single Campus Award (up to $300K over 2 years). The initiative anticipates awarding up to four Multi-Campus Partnership Awards and up to 10 Single Campus Awards in 2023. For more information, please view/download the full RFP.

Deadline: Tuesday, Aug. 15, 2023, at 6 p.m.
 
Notice of Special Interest: Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program (BRCP) - U.S. Entity (Admin Supp) (NOT-NS-23-092)
The National Institutes of Health (NIH) announces the continuation of the U.S. entity of the U.S.-Japan Brain Research Cooperative Program (BRCP). This administrative supplement program will provide funds to currently active research grants that are currently supported by one of the participating NIH Institutes and Centers. This Notice is soliciting administrative supplements for the following mechanisms ONLY: 
DP1DP2DP5R00R01R03R21R33R34R35R37R61RM1U01UH2 and UH3.

The purpose of the BRCP is to promote scientist exchange, training, and collaborations in basic, translational and clinical research between neuroscientists from the U.S. and Japan.

The U.S. entity of the BRCP supports the following activities:
1) Visit of U.S. scientists to conduct collaborative research and/or to acquire advanced research skills at institutions in Japan.
2) Joint workshops to exchange scientific information and to foster collaborations.

​​​​​​​View the NOSI here.

First Available Deadline: Monday, Sept. 18, 2023
Expiration Date: Sept. 19, 2025
 
Postdoctoral Funding Opportunity! A.P. Giannini Foundation Fellowship
The A.P. Giannini Foundation invites physician-scientists and junior researchers with 3 to 36 months of postdoctoral research experience (as of Dec. 31, 2023) to apply to the 2024 Postdoctoral Research Fellowship & Leadership Award.

The Fellowship and Leadership Award supports innovative research in the basic sciences and applied fields and trains fellows to become established investigators and to pursue scientific leadership positions in academia, industry, public and non-traditional career pathways. Research projects should advance the translation of biomedical science into preventions, treatments and cures for human diseases. Applicants with tenure-track research positions or faculty appointments are ineligible.

Fellows receive a competitive stipend for their research training. Candidates may be eligible to obtain additional salary support from their sponsoring institution. Fellows cannot concurrently hold a full fellowship from another source or a federally funded career development award. Fellows receive leadership training and support to maximize their postdoctoral experience. Fellows participate in workshops and receive one-on-one coaching to foster their communication and leadership skills. The Foundation requires that fellows participate in the Leadership Program.

For questions about the application process, reach out to Dr. Leslie Thompson (lmthomps@hs.uci.edu).

Deadline: Thursday, Nov. 9, 2023, 3 p.m.
 
For More Funding Opportunities
For more funding opportunities and resources for your funding search, visit the Funding Opportunities page on the new and updated website for the UCI School of Medicine.

For a curated, searchable and filterable list of funding opportunities by NIH in their weekly NIH guide listserv, check out the School of Medicine Funding Search Tool.
Upcoming Seminars & Events
 
NCI Drug Development Workshop II: Specialized Topics in Preclinical Development of Small Molecule Cancer Drugs
This workshop will encompass a series of six webinar-based lectures. They will address specialized topics that are important for the preclinical development of small molecule cancer drugs. The intention is to help investigators mitigate the translational risk of selected candidates during their later stages of product development and increase the chances of entering clinical evaluation. The intended audience is translational scientists who are interested in preclinical development of cancer drugs. Junior faculty, staff and trainees are encouraged to attend this workshop. Sessions start at 10 a.m. PT, and includes 60–90 minutes of lectures and 15 minutes of facilitated discussion. View the agenda for more information about this workshop.

July 27 and 28, 10 a.m. PT
Register
 
UCI Susan Samueli Integrative Health Institute's Research Speaker Series
The UCI Center for Neural Circuit Mapping and Acupuncture Research with Xiangmin Xu, PhD, professor in the Department of Anatomy and Neurobiology, director of the UCI Center for Neural Circuit Mapping.  

Wednesday, Aug. 2, noon
Register
 
Making a Difference in Human Subjects Research: Empowering Participants, Engaging Communities, and Protecting Data
​​​​​​Interested in spending two informative days with the HHS Office for Human Research Protections (OHRP) and your fellow colleagues in the human research protection world? If so, make plans to attend this in-person event, highlighting the ethical challenges and opportunities presented by AI technologies and innovations in academic-community partnerships.

Be sure to check out the 
line-up of speakers which includes experts from the NIH Office of Science Policy (OSP). Don’t miss this valuable and engaging opportunity to share challenges and learn best practices on how to manage, share and protect research data from HHS experts and your institutional colleagues.

Sept. 26–27, 2023 
Location: Ann Arbor, Michigan 
Register
 
Grand Rounds and CME Symposia
For Continuing Medical Education (CME) opportunities, view the weekly Grand Rounds & CME Symposia email.
Research Resources
 
Case Study in Research Integrity – Banned From Supervising, Can’t Go in Lab, but No Impact on NIH Funded Research?
NIH has seen rising numbers of allegations related to harassment, discrimination and hostile work environments since 2018 (when NIH first started tracking them). In many cases, NIH successfully works with recipient institutions to put appropriate measures in place to address unsafe working environments. However, too often NIH hears from institutions that a PI has violated the institution’s policies and is no longer permitted to supervise students or staff, but there will be “no impact on NIH-funded work.” NIH has a problem with this response. Read the full post.
 
What kind of grant support does the Research Development Unit (RDU) provide?
 
NIH Biosketch Info Session Recording
The Research Development Unit (RDU) recently held a NIH Biosketch info session. View the recording and slide deck. If you have any questions or would like the RDU to review your biosketch to ensure compliance, please email somrd@hs.uci.edu.
 
Are you considering applying for Limited Funding Opportunities?
In most cases, interested applicants submit a pre-proposal to the Office of Research where a committee reviews all submissions and makes a recommendation to the Vice Chancellor for Research about which proposal should go forward from UCI. Limited opportunities are advertised on fundopp.uci.edu with a link to apply. However, if you do not see a limited opportunity listed, please contact the Research Development Unit. We can relay your application plans to the UCI Office of Research so they are aware of the number of interested PIs/units on campus and, if necessary, coordinate PIs or create a review process.
 
Intramural & Foundation Funding Opportunities Lists
The Research Development Unit (RDU) has created lists of intramural funding opportunities and foundation funding opportunities. If you have additional opportunities that should be included, please do not hesitate to email at somrd@hs.uci.edu.
COVID-19 Information
 
UCI’s COVID-19 information hub, UCI Forward, has been retired. All employee-related information has migrated to the Human Resources Working Well webpage, and student-related information has moved to the Student Health Center webpage. For UCI Health updates, please visit UCI Health's COVID-19 page on SharePoint.
Contribute to Research Insider!
 
Submit your funding opportunities and events to next week's email here: Seminar/Event or Funding Opportunity.
© 2023 The Regents of the University of California. All rights reserved.