Background:
The UCI Department of Pathology & Laboratory Medicine, Microbiology Division will no longer offer the Anti-streptolysin O Titer by latex agglutination. The company, Fisher Scientific, is no longer manufacturing the SURE-VUE ASO test kit. The test can still be ordered and samples will be forwarded to our reference laboratory, ARUP. The test result should be available in two to three days. The test is used to confirm a prior infection with group A Streptococcus in patients suspected of having a nonsuppurative complication such as acute glomerulonephritis or acute rheumatic fever. Streptolysin O Antibody (ASO) and DNase-B Antibody (test code: XADB) antibody tests are generally ordered concurrently.
Effective date: Immediately
Test Methodology: Quantitative Nephelometry
Reference Interval:
0-1 year: 0-200 IU/mL
2-12 years: 0-240 IU/mL
13 years and older: 0-330 IU/mL
Discontinued test code: SERASO
New test code: TBD
Specimen requirements:
Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube.
Minimum volume: 0.4 mL
Stability (after separation from cells):
Ambient: 8 hours
Refrigerated: 8 days
Frozen: 3 months
Turnaround time (TAT) after receipt: within 24 hours
Rejection criteria:
Specimens that exceed stated stability, unlabeled/mislabeled/mismatched specimens, specimens submitted in leaking containers, non-sterile containers, hemolyzed specimens.
For additional information: http://www.aruplab.com/testing
Sincerely,
Cassiana Bittencourt, MD
Director
Division of Clinical Microbiology
Edwin S. Monuki, MD, PhD
Chair
Department of Pathology & Laboratory Medicine
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