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Lactate Dehydrogenase Reference Interval Update
Background:
The Department of Pathology & Laboratory Medicine will update the reference interval for lactate dehydrogenase (test code LDH) to 96-199 U/L. This reference interval was established in-house in 66 healthy blood donors.

Test Previous Reference
Interval (U/L):
Updated Reference
Interval (U/L):
Lactate Dehydrogenase
140-271
96-199

Effective date: May 26, 2021

Specimen requirement and testing information:

Specimen required: 1 mL of plasma or serum. Collect 4 mL of blood in green-top (lithium heparin), gold- top, or red-top tube. Spin down and separate serum or plasma within 2 hours of collection.

Test methodology: Enzymatic Rate

Test code: LDH

Minimum stability:
Ambient: 8 hours
Refrigerated: 2 days
Frozen: Unacceptable

Turnaround time (TAT):
STAT: 60 minutes
Routine: 2-4 hours
Set Up Days: Daily

Rejection criteria:
Specimens that exceed stated stability, unlabeled/mislabeled/mismatched specimens, and specimens submitted in leaking containers, or specimens received with insufficient amounts for testing. Clotted specimens.

A summary of all tests offered by our laboratory services can be found here: http://www.pathology.uci.edu/services/index.asp

Sincerely,

Bridgit O. Crews, PhD, DABCC
Director
Clinical Chemistry, Toxicology, & Point of Care Testing

Edwin S. Monuki, MD, PhD
Chair, Department of Pathology & Laboratory Medicine

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