Background:
In an effort to improve availability and turnaround time for Intact Parathyroid Hormone (PTH), the Department of Pathology & Laboratory Medicine is transferring testing for routine PTH to the Beckman Access Intact PTH assay. PTH levels below 40 pg/mL measure on average 8 pg/mL higher with this method compared to the previous method. The bias observed for higher levels of PTH is insignificant. This update does not affect testing for intraoperative PTH (RPTH), which is a separate test.
Adult reference intervals will remain the same. Specific ranges will be updated for pediatric ages.1, 2
| Test Name |
Previous Reference Intervals: (pg/mL) |
New Reference Intervals:
(pg/mL) |
Pediatric Intervals: |
0 to < 1 Year: 10 – 112
1 to 2 Year: 10 – 71
3 to 9 Year: 12 – 120
10 to 12 Year: 13 – 85
13 to 14 Year: 10 – 117
15 to 18 Year: 13 – 100 |
0 to < 1 Year: 7 – 58
1 to < 8 Years: 12 – 55
8 to < 19 Years: 12 – 71 |
| Adult Interval: |
10 – 68 |
10 – 68 |
Effective date: April 22, 2020
Specimen requirement and testing information:
Specimen: Serum (Red) / Plasma (EDTA)
Test methodology: Chemiluminescence
Test code: PTH
Minimum stability (after separation from cells):
Ambient: 2 hours
Refrigerated: 8 hours
Frozen: 6 months
Some tests may have extended stability beyond stated minimum limits. See directory for details.
Turnaround time (TAT):
STAT: N/A
Routine: 2 – 4 hours
Set Up Days: Daily
Rejection criteria:
Samples containing particulate matter and lipemic or hemolyzed specimens. Specimens that exceed stated stability, unlabeled/mislabeled/mismatched specimens, specimens submitted in leaking containers, or specimens received with insufficient amounts for testing.
Click here to see references
A summary of all tests offered by our laboratory services can be found here: http://www.pathology.uci.edu/services/index.asp
Sincerely,
Bridgit O. Crews, PhD, DABCC
Director
Clinical Chemistry, Toxicology, & Point of Care Testing
Edwin S. Monuki, MD, PhD
Chair
Department of Pathology & Laboratory Medicine |
